Since tires rarely self-destruct, there is always a smoking gun, and it’s in your best interest to find it. You do that through failure analysis.
Source: What’s Wrecking Your Tires?
It would have been nice if this very interesting article about tire wear and it’s effects covered how bad wear or failures effect fuel consumption and gas mileage from the vehicle as well.
I asked the question and I hope to have an answer soon.